Research Article

Utility of p-Chloranilic Acid and 2,3-Dichloro-5,6-dicyano-p-benzoquinone for the Spectrophotometric Determination of Rizatriptan Benzoate

Table 2

Regression and analytical parameters.

Parameterp-CA method DDQ method

λ max, nm530590
Beer’s law limits (μg mL−1) 14–2454–70
Molar absorptivity (l mol−1 cm−1)1.30 × 1035.22 × 103
Sandell sensitivity* (μg cm−2)0.30020.0751
Limit of detection (μg mL−1)1.360.60
Limit of quantification (μg mL−1)4.111.83
Regression equation,
 Intercept,( )0.00770.0078
 Slope,( )0.00320.0127
 Correlation coefficient ( )0.99990.9999
 Standard deviation of intercept ( )0.003360.00402
 Standard deviation of slope ( )0.000020.00009

*Limit of determination as the weight in μg per mL of solution, which corresponds to an absorbance of = 0.001 measured in a cuvette of cross-sectional area 1 cm2 and = 1 cm. ** , where is the absorbance, is the intercept, is the slope, and is the concentration in μg mL−1.