686952.fig.003
Figure 3: Effect of a high-fat diet and treatment with AVE7688 on thermal nociception and intraepidermal nerve fiber profiles in the hindpaw. Rats were fed a standard or high-fat diet with or without AVE7688, Enalapril or Candoxatril for 24 weeks. Data are presented as the mean ± SEM for thermal nociception in sec and intraepidermal nerve fiber profiles per mm. The number of rats in each group was the same as shown in Table 1. , compared to rats fed the standard diet (control), , compared to rats fed the high -fat diet.