Antioxidative Strategy for Inflammatory Diseases
1China Medical University, No. 91, Hsueh-Shih Road, Taichung 404, Taiwan
2University of California, Irvine, Department of Medicine, Med Sci 1, C240, Irvine, CA 92697, USA
3Khon Kaen University, 123 Muang District, Khon Kaen 40002, Thailand
4National Taiwan University, No.1, Section 1, Jen-Ai Road, Taipei 100, Taiwan
Antioxidative Strategy for Inflammatory Diseases
Description
Cellular oxidants are unique classes of signaling messengers control signal transduction events to drive desirable cellular and biological responses, such as inflammatory cytokine production. However, imbalance oxidative stress causes both cellular and biological damages. Thus, it is reasonable to counterbalance oxidative stress to treat inflammation-related diseases by modulating reactive oxygen species production. Such antioxidative therapeutic strategies include various endogenous and exogenous antioxidative enzymes, antioxidants, and radical scavengers.
This special issue will allow clinicians and researchers to summarize the recent ideas with respect to the regulation of oxidative stress and provide the antioxidative therapeutic and delivery strategy for inflammatory diseases. In addition, this special issue aims to inspire novel antioxidant/drug development targeting the cellular reduction-oxidation (redox) networks to treat inflammatory diseases. Potential topics include, but are not limited to:
- Therapeutic strategies by modulating oxidative stress in inflammatory diseases
- Development of antioxidants (enzymes, phytomedicines, nutrients, or radical scavengers) for inflammatory diseases
- Cellular redox networks and free radical biology in inflammation
- Oxidative biomarkers for inflammatory diseases
- Oxidative stress in immune cell proliferation and death
- Redox-sensitive signal transduction pathways receptor, kinase, and transcription factor (such as Nrf2, NF-κB, or AP-1) cascades) in inflammation
Before submission authors should carefully read the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Authors should submit an electronic copy of their complete manuscript through the Journal Manuscript Tracking System http://mts.hindawi.com/submit/journals/mi/asid/ according to the following timetable: