A Sphingosine Kinase Form 2 Knockout Sensitizes Mouse Myocardium to Ischemia/Reoxygenation Injury and Diminishes Responsiveness to Ischemic Preconditioning

<table>Levels of phospho-Akt (P-Akt) and phospho-p38 (P-p38) in wild-type (WT), heterozygous (HET), and SphK2-knockout (KO) mouse hearts. P-Akt and P-p38 levels were determined by Western analysis in the cytosolic fractions from 4 KO hearts (lanes 1–4), 4 WT hearts (lanes 6–9), and 1 HET heart (lane 5).  GAPDH: glyceraldehyde phosphate dehydrogenase.</table>

Oxidative Medicine and Cellular Longevity

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Figure 5

Figure 5: A Sphingosine Kinase Form 2 Knockout Sensitizes Mouse Myocardium to Ischemia/Reoxygenation Injury and Diminishes Responsiveness to Ischemic Preconditioning 

Figure 5 | A Sphingosine Kinase Form 2 Knockout Sensitizes Mouse Myocardium to Ischemia/Reoxygenation Injury and Diminishes Responsiveness to Ischemic Preconditioning 