308358.fig.001
Figure 1: Liver status of the glutathione metabolism in the control group, the endothelin-1 groups, (1.25 and 12.5 μg/kg/b.w.) and BAY 11-7082 (10 mg/kg b.w.) administered 1 hour before ET-1 (12.5 μg/kg b.w.) group ( , per group). Data is shown as mean ± S.E.M. ET-1-endothelin-1 at doses of 1.25 and 12.5 μg/kg b.w.; BAY+ET-1-BAY 11-7082 (10 mg/kg b.w.) administered 1 hour before endothelin-1 (12.5 μg/kg b.w.) group; tGSH-total glutathione; GSH-reduced glutathione; GSSG-oxidized glutathione. , , , and   versus saline; , , , and   versus BAY 11-7082 + ET-1; ,   versus ET-1 (1.25 μg/kg b.w).