A Human Hepatocyte-Bearing Mouse: An Animal Model to Predict Drug Metabolism and Effectiveness in Humans
Figure 2
Close natural apposition of m-stellate cells and h-hepatocytes in a chimeric liver. A serial section shown in Figure 1 was doubly stained with -CK8/18 (green) for h-hepatocytes and m-desmin (orange) for m-stellate cells. The h-hepatocytes are well organized and closely apposed to m-stellate cells in Disse’s space. Arrows indicate representative h-hepatocytes (green) and m-stellate cells (orange). Bar, .
