Review Article
Prevention and Treatment of Venous Thromboembolism with New Oral Anticoagulants: A Practical Update for Clinicians
Table 4
Approved indications of new oral anticoagulants in USA, Canada, and Europe.
| ā | Dabigatran | Rivaroxaban | Apixaban | Edoxaban |
| Prevention of venous thromboembolism after major orthopedic surgery
| Canada, Europe | USA, Canada, and Europe | Canada, Europe | Japan | Prevention of systemic thromboembolism in nonvalvular atrial fibrillation
| USA, Canada | USA, Canada, and Europe | USA, Canada, and Europe | NA | Treatment of acute DVT/PE and prevention of recurrent VTE | NA | USA, Canada*, and Europe* | NA | NA |
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DVT: deep venous thrombosis, NA: not applicable, PE: pulmonary embolism.
*Only for treatment of acute DVT and prevention of recurrent VTE.
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