Targeting FASN in Breast Cancer and the Discovery of Promising Inhibitors from Natural Products Derived from Traditional Chinese Medicine

Table 4

Herbs with regulating Qi flow’s function with strong FASN inhibitory effect. The stagnation of Qi, one of the most important material bases in human body according to TCM theory, will result in a lot of different diseases including malignancy. Therefore, regulating the Qi flow is an important strategy in diseases treatment and in malignancy treatments; this group of herbs is usually used in combination with those stated in Tables 2 and 3.

理 氣 Regulating QI flow	Chemical components	Pharmacological action
Illicium verum Hook. f. (八 角茴 香)	Fatty oils; Anise oil; Resin; Quercetin; Kaempferol	Antitumor; elevation of white blood cells; bacteriostat; promote digestion
Lindera strychnifolia (Sieb. et Zucc.) F.-Vill (烏 藥)	Essential oils; borneol; Furan sesquiterpene; Alkaloid; Neolinderalactone; Linderane	Antitumor; promote intestinal peristalsis; promote the secretion of digestive juice; antibiosis
Rosa rugosa Thunb. (玫 瑰花)	Essential oils; Citronellol; Vernol; Phenylethyl acetate; Isoquercitrin; Tannins; Gallic acid	Antitumor; immunoregulation
Fructus Amomi (砂 仁)	Bomyl acetate; Camphor; Limonene; nerolidol; Cineole; Flavonoids	Antitumor; bacteriostat
Areca catechu L. (檳 榔)	Tannins; Alkaloid; Arecoline; Arecaidine; Catechin; Epicatechin; Myristic acid; Lauric acid; Palmitic acid; Oleic acid; Linoleic acid	Antitumor; expelling parasite; antiviral; antifungal