Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model
Figure 2
Serotonin cells in the raphe nucleus of 7-month-old control and S100B transgenic mice. In (a), a representative photomicrograph is shown to illustrate the 5-HT immunohistochemical labeling of serotonin cells in the raphe nuclei. In (b), a graph of the means showing no significant differences in the number of serotonin neurons between CD-1 control and S100B transgenic mice in the dorsal, median, and caudolinear segments of the raphe nucleus. It is pertinent to note that when all three regions were combined, the data were still not significantly different (data not shown).
