Research Article
Treatment of Chronic Hepatitis C Virus Infection in Dialysis Patients: An Update
Table 1
Treatment with alpha-interferon or pegylated-alpha interferon in dialysis HCV positive patients: results from 3 meta-analyses.
| | Meta-analysis 1 (Fabrizi et al. [16]) | Meta-analysis 2 (Gordon et al. [17]) | Meta-analysis 3 (Alavian and Tabatabaei; [18]) |
| Number of studies | 28 | 25 | 33 | Number of patients | 645 | 459 | 770 | Overall SVR (standard IFN/Peg-INF) % | 39/41 | 41/37 | 39.1/39.3 | Genotype 1(%) | 33 | Not reported | Not reported | Treatment discontinuation (standard IFN/Peg-IFN/Placebo) % | 19/27/ not reported | 26/28/22 | 22.6/29.7/not reported |
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SVR: sustained virological response; IFN: alpha-interferon; Peg-IFN: pegylated alpha-interferon.
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