Clinical Study
Tumor Necrosis Factor Receptor 1 Expression Is Upregulated in Dendritic Cells in Patients with Chronic HCV Who Respond to Therapy
Table 4
(a) TNFR1 mRNA Levels in genotype 1 SVR during IFN based therapy. (b) TNFR1 levels in genotype 1 non-responders/relapsers during IFN-based therapy.
(a) |
| | week 0 | week 4–12 | 14–24 wks | 25–48 wks |
| Patient 1 | 0.96 | 7.83 | | | Patient 2 | 1.39 | 7.13 | 1.97 | 0.71 | Patient 3 | 4.23 | | 7.61 | 3.86 | Patient 4 | | | 8.44 | 23.48 | Patient 5 | 0.15 | | 0.63 | | Patient 6 | 6.42 | | 19.77 | 11.73 | Patient 7 | | | 0.87 | 0.82 | Patient 8 | | | 0.29 | 1.45 | Patient 9 | | | 0.15 | 11.46 | Patient 10 | | | 1.24 | 1.52 | Patient 11 | 0.43 | | 35.93 | 8.04 | Patient 12 | 0.06 | | | 18.20 | Patient 13 | | 0.29 | 0.22 | |
|
|
(b) |
| | week 0 | week 4–12 | 14–24 | 25–48 |
| Patient 1 | 1.53 | 4.73 | | | Patient 2 | 0.67 | | 1.14 | | Patient 3 | 2.73 | | 0.17 | | Patient 4 | 2.61 | | | 0.98 | Patient 5 | 2.97 | | 6.54 | | Patient 6 | 0.64 | 4.07 | | 0.16 | Patient 7 | | | 1.25 | 2.71 | Patient 8 | 2.83 | | 1.20 | 0.34 | Patient 9 | 0.26 | | 0.10 | 0.11 | Patient 10 | | | 0.73 | 0.15 | Patient 11 | | | 0.08 | 0.05 | Patient 12 | | | 0.46 | 0.14 |
|
|