Effect of cNOS inhibitors on the ghrelin (Gh)-induced changes in apoptosis and cNOS activity in the acinar cell exposed to P. gingivalis LPS. The cells, preincubated with 20 $\mu$M PP2, 30 $\mu$M SH-5 (SH), 300 $\mu$M ascorbate (As), or 400 $\mu$M L-NAME (LN), were treated with Gh (at 0.6 $\mu$g/mL) and incubated for 16 hours in the presence of 100 ng/mL LPS. Values represent the means $\pm$ SD of five experiments. ${}_{}{}^{*}P<.05$ compared with that of control. ${}_{}{}^{**}P<.05$ compared with that of LPS alone. ${}_{}{}^{***}P<.05$ compared with that of Gh + LPS.