Evolution and Prospects for Intracranial Pharmacotherapy for Refractory Epilepsies: The Subdural Hybrid Neuroprosthesis
Figure 4
Penetration of methylene blue molecules from the epidural delivery site through the subdural space into the motor cortex, in a rat. Coronal section of a formalin-fixed brain is shown; the concentration of the methylene blue solution was 1%. Note the limited cortical area of diffusion.
