Research Article

Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo

Table 1

Comparison of average rate of nonsynonymous (dN) and synonymous (dS) substitutions with standard errors obtained through 1000 bootstrap replicates in parentheses for the peptide-binding region (PBR) and non-peptide binding region (non-PBR) and their ratio among different BoLA-DRB3 alleles. : number of codons.

AllelesNo allelesPositions d (K2p)dN (SE)dS (SE)dN/dS

Indian cattle22PBR220.283(0.042)0.332(0.064)0.139(0.050)2.38.008
Non-PBR560.069(0.012)0.074(0.018)0.055(0.018)1.34.211
All780.123(0.014)0.137(0.022)0.076(0.019)1.80.009
BoLA alleles89PBR220.256(0.041)0.311(0.072)0.102(0.039)3.05.003
Non-PBR560.035(0.008)0.039(0.013)0.019(0.013)2.05.140
All780.090(0.012)0.105(0.021)0.041(0.014)2.56.002
Sheep55PBR220.176(0.033)0.223(0.062)0.041(0.025)5.43.001
Non-PBR560.042(0.009)0.045(0.013)0.037(0.014)1.211.000
All780.077(0.011)0.087(0.018)0.045(0.014)1.93.019
Goat20PBR220.218(0.038)0.269(0.067)0.065(0.031)4.13.001
Non-PBR560.058(0.011)0.062(0.015)0.046(0.017)1.34.200
All780.099(0.013)0.114(0.019)0.050(0.014)2.28.002
Buffalo28PBR220.238(0.039)0.277(0.067)0.120(0.064)2.30.025
Non-PBR560.079(0.013)0.065(0.014)0.126(0.031)0.511.000
All780.118(0.014)0.127(0.021)0.097(0.020)1.301.000
Big horn sheep21PBR220.224(0.042)0.294(0.073)0.033(0.018)8.90.000
Non-PBR560.045(0.010)0.046(0.012)0.044(0.020)1.04.470
All780.090(0.013)0.106(0.019)0.041(0.015)2.58.005
White tailed deer15PBR220.254(0.046)0.327(0.079)0.061(0.028)5.36.000
Non-PBR560.062(0.011)0.065(0.015)0.054(0.021)1.20.286
All780.110(0.014)0.128(0.023)0.055(0.016)2.32.002
Red deer24PBR200.235(0.038)0.282(0.068)0.108(0.045)2.61.007
Non-PBR550.064(0.011)0.067(0.016)0.055(0.022)1.21.126
All750.105(0.013)0.117(0.022)0.068(0.019)1.72.003