Molecular Biology International / 2011 / Article / Tab 2 / Research Article
Allelic Diversity of Major Histocompatibility Complex Class II DRB Gene in Indian Cattle and Buffalo Table 2 Interspecies comparison of polymorphic amino acid substitutions for DRB exon 2 molecules in cattle, sheep, goat, buffalo, red deer, white-tailed deer and big horn sheep. The bottom row indicates the number of sequences examined in each species (*in the amino acid position column indicates that this position forms part of the peptide binding groove according to the model of Brown et al. 1993).
Codon position Alleles of Indian cattle BoLA alleles Sheep Goat Buffalo Red deer White-tailed deer Big horn sheep
*09 EQ EQ E ER EQ EL ESV E 10 Y Y Y Y Y HQY HY Y
*11 ACHLST ACHLRSYT AHRSYT CHSTY ARSVY AFHLPST AFGHP AHRTY 12 KT KQT KRT KT KT KT K K
*13 GKRS GKRS KRS AGKRS GKRS AGRS AGKS GKS 14 E E E E EG E E E 15 C C C C C C C C 16 H H HR H H HPY H HR 17 F F F F F F F F 18 F F FS FS FS FPS S FS 19 N DN N N N N N N 20 G G G G G G G G 21 T T T T T T T T 22 E E E EGQ E EQ EQ E 23 R R R R R R R R 24 V LV V V V MV V V 25 R QR RW GRW QRW GQR QR R 26 FLY FLY FLY FLY FLY FLSY FLY FLY 27 L L L L LR L L L
*28 DEH DEHN DE DH DEQ ADEGQ DEFQV DEH 29 R R R R GR R R R
*30 CHSY CHSY Y Y HY Y DY FY 31 FY FY FY FY FIY FIV FIV FY
*32 HTY HTY HTY HTY STY CHY Y HTY 33 N N N N N KNS N N 34 G G G G G EGRW GKQR G 35 E E E E EK E E E 36 E E E E E EG E E
*37 FHLNRTY FHLNRTY FNTY FINTY LNTY FY FIY FNTY
*38 AV AV ALV LV LV AV LV AV 39 R R R R TR R R R 40 F F F FY F FY FY F 41 D D D D D D D D 42 S S NS NS GS CS S NS 43 D D D D D D DN D 44 W W W RW QRW VW V W 45 DG DGS GS G G G G G 46 E E E E E EQ E E
*47 FY FY FY FY FY FY FY FY 48 QR QRW R R R QR R R 49 A AE AP A A A A A 50 V LV V V LV V V AV 51 T T AT AT T T T AT 52 E E E E E EK E EQ 53 L L L LQ L L L LQ 54 G G G G G G G G 55 RW PQR R RQ PQR R QR QR
*56 PR PQR PQR EPQ PQ P PT EPR 57 ADSV ADSV AEDS DENST DIS DSV DES ADS 58 A AR AV A A A A A 59 EKV EKV EK EK EK EK DEK EK
*60 HQY HLQY HQY Y DLQY HY DGNY HY
*61 LW CLW W W W LWY FWY W 62 N N N N N N N N 63 GS GS S S GS S RS S 64 Q Q Q Q Q LQR QR Q 65 K K K K EK K K K 66 DE DE DEN DE DG E DE DE 67 FILT FILT FIL FIL FI ILY FIL FIL 68 L L L L L LM L L 69 E E E E E E E E
*70 DEQR DEQR QRS DQNRS DQR DEQR DEQRY QRS
*71 AEKR AEK AKRT KRS KQRS AEHKLNRT KLNRSW AKRT 72 R R R R R GR R R 73 A A APT AT AW A AT A
*74 AENSY AENSY AENT AENS AENST AEN AELS AEN 75 V V V AV V V AV V 76 D D DN D D D D D 77 RT RT T KT AGKRST RT T RT
*78 VY VY VY FVY FVY FVY VY VY 79 C C C C C C C C 80 R R R R R R IRS R
*81 H HY H HY HY HY H HR
*82 N N N DNY N DN N N 83 Y Y Y Y Y Y SY Y 84 G G G G GR G G
*85 GV GV V V V IV V
*86 GV FGMV FGID FGILV DFGV FGI FGIV
