Organic Chemistry International
Volume 2011 (2011), Article ID 170196, 35 pages
Review Article

A Review on the Chemistry of Eremanthine: A Sesquiterpene Lactone with Relevant Biological Activity

Departamento de Química, Instituto de Ciências Exatas, Universidade Federal Rural do Rio de Janeiro, 23890-970 Seropédica, RJ, Brazil

Received 10 December 2010; Accepted 2 February 2011

Academic Editor: Bill Baker

Copyright © 2011 José C. F. Alves. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The several aspects on the chemistry of eremanthine such as isolation, structural classification, biological activity, synthesis, and chemical transformations in other sesquiterpene lactones are described in this review. The main publications on this sesquiterpenolide, from its isolation of natural sources in 1972 to the current days, are included.