International Scholarly Research Notices

Review Article

Airway Epithelium in Atopic and Nonatopic Asthma: Similarities and Differences

Table 1

Comparison of bronchial epithelial components in atopic and nonatopic asthma.
Cell types or epithelial componentsAtopic asthmaNonatopic asthma
Ciliated columnarDamage ++Damage + [23, 24]
DesmosomesBreakdown ++Breakdown + [23]
GobletHyperplasia +Hyperplasia − [23]
Basal cellsDamage +/−Damage +/− [23]
Basement membraneThickening ++Thickening + [23, 24, 28–30]
EosinophilsInfiltration +++Infiltration +++ [20, 24, 33]
NeutrophilsInfiltration +Infiltration ++ [24, 34]
Mast cellsInfiltration ++Infiltration + [23]
LymphocytesInfiltration +++Infiltration ++ [21, 23, 24]
MacrophagesInfiltration +Infiltration ++ [20–22]