Review Article
Airway Epithelium in Atopic and Nonatopic Asthma: Similarities and Differences
Table 2
Cytokine and cytokine receptor expression in the respiratory epithelium and submucosa.
| | Cytokines and receptors | Atopic asthma | Nonatopic asthma |
| | Th1 | γ IFN (sputum) | ++ | ++ [39] | | IL-2 (BAL fluid) | + | ++ [38] | | IL-2R+ | + | + [38] |
| | Th2 | IL-4 | ++ +/− | ++ [8] | | IL-4α receptor | ++ | ++ [8] | | IL-5 | ++ +/− | ++ [8] | | IL-5α receptor | ++ | ++ [8] | | IL-10 (sputum) | ++ | + [40] | | IL-13 | ++ | ++ [37] | | GMCSF | ++ | ++ [37, 39] |
| | Th1 & Th2 | IL3 | ++ | ++ [37] |
| | Macrophage | GMCSFR-α | + | +++ [22] |
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