(a) Gallbladder swelling cannot be seen on baseline abdominal CT before sorafenib administration. (b) A highly tense and enlarged gallbladder can be seen on abdominal CT. There is no thickening of the gallbladder wall. The intrahepatic and common bile ducts are not dilated, and there are no calculi in the gallbladder or tumorous lesions in the neck of the gallbladder.