Review Article

Small Changes Huge Impact: The Role of Protein Posttranslational Modifications in Cellular Homeostasis and Disease

Table 1

Comparative analysis shown for 20 amino acids with possible functional modification(s) observed for each amino acid residue. For more information, refer to the text and citations therein.

Amino acidsAcetylationCarbonylationGlycosylation and glycationHydroxylationMethylationNitrationPalmitoylationPhosphorylationSulfationUbiquitination

Alanine
Isoleucine
Leucine
Valine
Phenylalanine
Tryptophan
Tyrosine
Asparagine
Cysteine
Glutamine
Methionine
Serine
Threonine
Aspartic acid
Glutamic acid
Arginine
Histidine
Lysine
Glycine
Proline