Research Article
Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique
Table 2
Results of factorial design batches ().
| | Parameter | | | | | | | | | |
| | Assay (%) | 93.45 | 97.43 | 92.50 | 91.45 | 94.62 | 96.08 | 95.2 | 92.74 | 97.6 | | Friability (%) | 0.162 | 0.198 | 0.190 | 0.112 | 0.105 | 0.107 | 0.043 | 0.067 | 0.0982 | | Hardness (Kg/cm2) | 3.25 | 3.5 | 3.0 | 2.75 | 3.75 | 4 | 3.75 | 3.25 | 3.75 | | Similarity factor () | 28.69 | 38.03 | 29.12 | 30.67 | 32.05 | 40.99 | 72.22 | 43.46 | 70.64 |
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