Research Article

Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique

Table 4

Calculations for testing the model in portions.

DFSSMSFR2
𝑄 1

Regression Fcalc. = 0.414
FM51295.88259.1762.0950.7774 Ftable = 5.34
RM11162.041162.04214.110.6684DF(4,3)
Error
FM3370.996123.665
RM7576.25182.322

𝑄 4

RegressionFcalc. = 0.417
FM5588.807117.761.480.7122Ftable = 5.34
RM1444.104444.1048.390.5453DF (4,3)
Error
FM3237.93679.31
RM7370.31752.9

𝑄 8

RegressionFcalc. = 0.197
FM538.4747.6948130.92110.6055Ftable = 5.34
RM111.0432 11.04322.440.2587DF (4,3)
Error8.353
FM325.059154.5191
RM731.6339

𝑛

RegressionFcalc.= 0.571
FM50.073280.01462.610.8135 Ftable=5.34
RM10.071280.0712816.880.7069DF(4,3)
Error
FM30.016790.005597
RM70.029550.004222

𝐾

RegressionFcalc.=0.439
FM50.16390.03272.210.7867Ftable=5.34
RM10.14780.147814.70.677DF (4,3)
Error
FM30.04440.0148
RM70.07040.0101

DF, degree of freedom; SS, sum of squares; MS, mean of squares; 𝑅 2 , regression coefficient; FM, full model; RM, reduced model.