Research Article
Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique
Table 4
Calculations for testing the model in portions.
| | DF | SS | MS | F | R2 | | | | | | | | |
| Regression | | | | | | Fcalc. = 0.414 | FM | 5 | 1295.88 | 259.176 | 2.095 | 0.7774 | Ftable = 5.34 | RM | 1 | 1162.04 | 1162.042 | 14.11 | 0.6684 | DF(4,3) | Error | | | | | | | FM | 3 | 370.996 | 123.665 | | | | RM | 7 | 576.251 | 82.322 | | | |
| | | | | | | |
| Regression | | | | | | Fcalc. = 0.417 | FM | 5 | 588.807 | 117.76 | 1.48 | 0.7122 | Ftable = 5.34 | RM | 1 | 444.104 | 444.104 | 8.39 | 0.5453 | DF (4,3) | Error | | | | | | | FM | 3 | 237.936 | 79.31 | | | | RM | 7 | 370.317 | 52.9 | | | |
| | | | | | | |
| Regression | | | | | | Fcalc. = 0.197 | FM | 5 | 38.474 | 7.694813 | 0.9211 | 0.6055 | Ftable = 5.34 | RM | 1 | 11.0432 | 11.0432 | 2.44 | 0.2587 | DF (4,3) | Error | | | 8.353 | | | | FM | 3 | 25.05915 | 4.5191 | | | | RM | 7 | 31.6339 | | | | |
| | | | | | | |
| Regression | | | | | | Fcalc.= 0.571 | FM | 5 | 0.07328 | 0.0146 | 2.61 | 0.8135 | Ftable=5.34 | RM | 1 | 0.07128 | 0.07128 | 16.88 | 0.7069 | DF(4,3) | Error | | | | | | | FM | 3 | 0.01679 | 0.005597 | | | | RM | 7 | 0.02955 | 0.004222 | | | |
| | | | | | | |
| Regression | | | | | | Fcalc.=0.439 | FM | 5 | 0.1639 | 0.0327 | 2.21 | 0.7867 | Ftable=5.34 | RM | 1 | 0.1478 | 0.1478 | 14.7 | 0.677 | DF (4,3) | Error | | | | | | | FM | 3 | 0.0444 | 0.0148 | | | | RM | 7 | 0.0704 | 0.0101 | | | |
|
|
DF, degree of freedom; SS, sum of squares; MS, mean of squares; , regression coefficient; FM, full model; RM, reduced model.
|