Research Article
Cytoplasmic Staining of TTF-1 Antibody in the Diagnosis of Hepatocellular Carcinoma: Study on 299 Cases Using Tissue Microarray
Table 5
Clinicopathologic correlations between biologic factors and patients with HCC.
| | Factor | No. reactive (No. evaluated) | Rate of expression | values |
| | Sex | | | | | Female | 13 (23) | 56.5% | | | Male | 152 (276) | 55.1% | |
| | Age | | | | | ≤35 y | 22 (40) | 55.0% | | | >35 y | 143 (259) | 55.2% | |
| | Serum AFP | | | | | ≤400 ug/l | 81 (157) | 51.9% | | | >400 ug/l | 84 (142) | 59.1% | |
| | Tumor size | | | | | Single and <3 cm | 11 (16) | 68.7% | | | ≥3 cm | 154 (283) | 54.4% | |
| | No. of nodules | | | | | 1 | 98 (178) | 53.9% | | | ≥2 | 67 (121) | 53.7% | |
| | Vein or bile duct tumor thrombus | | | | | Present | 54 (93) | 58.0% | | | Absent | 111 (206) | 53.8% | |
| | Edmondson-Sterner grade | | | | | I + II | 151 (234) | 64.5% | | | III + IV | 14 (65) | 21.5% |
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*
was considered statistically significant.
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