Research Article

Bioinformatic Analysis of Leishmania donovani Long-Chain Fatty Acid-CoA Ligase as a Novel Drug Target

Figure 6

Leishmania long-chin fatty acyl-CoA ligase model. (a) The larger left hand-side domain is the N-terminal domain and the smaller one is the C-terminal domain which is connected by a linker chain. (b) Superposition of the modeled structure of Leishmania long-chain fatty acyl-CoA ligase (Orange) with the crystal structure of the T. thermophilus long-chain fatty acyl-CoA synthetase (PDB code: 1ult A) (Blue).
278051.fig.006a
(a)
278051.fig.006b
(b)