Review Article
Occupational Asthma in Antibiotic Manufacturing Workers: Case Reports and Systematic Review
Table 1
Cases of occupational asthma from antibiotics identified at Royal Brompton Hospital in the period 1995–2009.
| | case | Year of diagnosis | Workplace exposure | Allergic symptoms | Latency | Specific IgE | Bronchial provocation test | | Agent | FEV1 response | Increase in histamine reactivity |
| | a | 1995 | penicillin | wheeze | 19 years | not done | penicillin | late | Yes | | b | 1996 | amoxicillin | wheeze, cough | 27 years | penicilloyl G (+)
penicilloyl V (+) | amoxicillin | late | yes | | c | 2000 | amoxicillin | wheeze, cough | 27 years | amoxicilloyl (+) | amoxicillin | late | yes | | d | 2009 | erythromycin | wheeze, rhinitis | 2 years | erythromycin ethylsuccinate (−) | erythromycin ethylsuccinate | late | Yes |
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