Tumor Vascular Morphology Undergoes Dramatic Changes during Outgrowth of B16 Melanoma While Proangiogenic Gene Expression Remains Unchanged
Figure 7
Summary of gain and loss of gene expression in the B16.F10 tumor vascular compartment of intermediate and large tumors compared to normal quiescent endothelium: gene expression in microdissected tumor endothelium from s.c. growing intermediate and large B16.F10 tumors (a total of 6 animals) and microdissected kidney venule endothelium from healthy C57bl/6 mice (10 animals). Red: detectable expression in more than 75% of all analyzed samples; yellow: detectable expression in 25–75% of all analyzed samples; green: expression of the gene could not be detected in the majority of the samples (less than 25% of positivity).
