Glycemic measure Brief definition Reference MBG Mean of all glucose values 5.7 mmol/L [20 ], 5.8 mmol/L [26 ] for healthy individuals SD SD of all glucose values 1 mmol/L [20 ], 0.8 mmol/L [26 ] for healthy individuals LAGE Blood glucose (BG)max -BGmin 1.4–5.7 mmol/L for healthy individuals [16 ] MAGE Average amplitude of upstrokes or downstrokes with magnitude greater than 1 SD 1.2–3.3 mmol/L for healthy individuals [6 ] M -valueWeighted average of glucose values, with progressively larger penalties for more extreme values 0 for healthy individuals, 0–18 for good control [7 ] MODD Mean difference between glucose values obtained at the same time of day on two consecutive days 0.3–0.5 mmol/L for healthy individuals, 0.6–2.0 mmol/L for stable diabetes [8 ]
𝐽
-index0.001 × (mean + SD)2 10 <
𝐽
< 20 as Ideal glucose control [9 ] HBGI High blood glucose index <4.5 for low risk of hyperglycemia [10 ] LBGI Low blood glucose index ≤1.1 for minimal risk [11 ] ADRR Range to predict both hypoglycemia and hyperglycemia <10 for low risk [12 ] GRADE score Weighted average of glucose values, giving a greater penalties to hypoglycemia than hyperglycemia, and to more severe departures from the target level of 5.8 mmol/L <5 reflects the euglycemic range [13 ] hypoglycaemia Percentage of GRADE score attributable to glucose values below 3.9 mmol/L [13 ] euglycaemia Percentage of GRADE score attributable to glucose values within the range 3.9–7.8 mmol/L [13 ] hyperglycaemia Percentage of GRADE score attributable to glucose values above 7.8 mmol/L [13 ] %CV
1
0
0
×
S
D
/Mean14 with range 13–16 for healthy individuals [27 ] IGC Sum of hyperglycemia index and hypoglycemia index [14 ] CONGA24 Measure of within-day glucose variability; SD of differences between any glucose value and another one exactly 24 hours latter [14 ] 24 hrs-AUC AUC attributable to glucose values above 2.2 mmol/L 135 mm
o
l
⋅
2
4 h/L for healthy individuals [20 ] PT > 7.8 mmol/L AUC attributable to glucose values above 7.8 mmol/L/24 hr-AUC 4% for healthy individuals [20 , 26 ] PT > 8.9 mmol/L AUC attributable to glucose values above 8.9 mmol/L/24 hr-AUC N/A PT > 10 mmol/L AUC attributable to glucose values above 10 mmol/L/24 hr-AUC
0
.
2
±
0
.
5
for healthy individuals [20 ]PT < 3.3 mmol/L AUC attributable to glucose values within the range 2.2–3.3 mmol/L/24 hr-AUC
1
±
1
for healthy individuals [20 ]
