Clinical Study

Glycemic Profiles of Healthy Individuals with Low Fasting Plasma Glucose and HbA1c

Table 2

CGM indicators of healthy subjects without diabetes.

Fasting blood glucose level
ALL
( 𝑁 = 2 9 )
<100
( 𝑛 = 2 2 )
100–126
( 𝑛 = 7 )
𝑃 -value

MBG (mmol/dL) 6 . 4 ± 0 . 8 6 . 4 ± 0 . 7 6 . 6 ± 1 . 1 0.471
SD (mmol/dL) 1 . 2 ± 0 . 4 1 . 2 ± 0 . 4 1 . 3 ± 0 . 4 0.562
LAGE (mmol/dL) 4 . 5 ± 1 . 6 4 . 4 ± 1 . 6 4 . 9 ± 1 . 8 0.414
MAGE (mmol/dL) 2 . 3 ± 0 . 8 2 . 2 ± 0 . 8 2 . 5 ± 0 . 7 0.388
𝑀 -value 7 . 3 ± 3 . 2 6 . 8 ± 3 . 1 8 . 8 ± 3 . 1 0.153
MODD (mmol/dL) 1 . 3 ± 0 . 5 1 . 3 ± 0 . 5 1 . 4 ± 0 . 5 0.593
𝐽 -index 1 9 ± 4 . 5 1 8 ± 3 . 9 2 1 ± 6 . 1 0.304
HBGI0.5 (0.3, 1.0)0.5 (0.3, 0.9)1.0 (0.3, 1.2)0.102
LBGI0.4 (0.2, 1.4)0.4 (0.2, 0.8)0.9 (0.2, 2.0)0.228
ADRR4.6 (2.6, 7.3)4.6 (2.6, 7.1)7.7 (4.1, 11.3)0.142
GRADE score 3 . 0 ± 1 . 3 2 . 7 ± 1 . 1 3 . 9 ± 1 . 4 0.022
hypoglycaemia0.0 (0.0, 0.1)0.0 (0.0, 0.1)0.0 (0.0, 0.2)0.446
euglycaemia 0 . 6 ± 0 . 2 0 . 7 ± 0 . 2 0 . 5 ± 0 . 2 0.044
hyperglycaemia 0 . 3 ± 0 . 2 0 . 3 ± 0 . 2 0 . 4 ± 0 . 2 0.130
CV %19.6 (11.9, 23.8)18.2 (11.9, 23.7)20.7 (11.4, 24.8)0.371
IGC1.6 (0.7, 3.6)1.7 (0.7, 3.6)0.8 (0.4, 8.2)0.460
CONGA24 1 . 1 ± 0 . 4 1 . 1 ± 0 . 4 1 . 1 ± 0 . 3 0.659
24 hrs-AUC (mmo l 2 4 h/dL) 1 5 5 ± 1 9 1 5 5 ± 1 9 1 6 0 ± 1 9 0.427
Percentage of time at glycemia (%)
 >7.8 mmol/L16% (5%, 27%)13% (3%, 23%)19% (7%, 30%)0.212
 >8.9 mmol/L1% (0%, 5%)1% (0%, 6%)3% (1%, 5%)0.238
 >10 mmol/L0% (0%, 1%)0% (0%, 1%)0% (0%, 0%)0.314
 < 3.3 mmol/L0% (0%, 0%)0% (0%, 0%)0% (0%, 2%)0.134

Presented by mean ± SD or median (25%, 75%) depending on the normality based on Shapiro-Wilk test.
𝑃 value was based on either 𝑡 -test or Wilcoxon sum rank test depending on the normality based on Shapiro-Wilk test.