Research Article
Development of Topical Niosomal Gel of Benzoyl Peroxide
Table 5
Table shows data of optimization of solvent system.
| Formulation code | Chloroform | Methanol | Volume of solvent system | Percentage drug entrapments ± %SD | Average particle size ± %SD |
| NF29 | 1 | 1 | 10 | 82.26% (±1.89) | 4.67 (±0.09) | NF30 | 2 | 1 | 10 | 56.55% (±1.98) | 5.23 (±0.21) | NF21 | 1 | 2 | 10 | 92.16% (±2.43) | 4.78 (±0.09) | NF31 | 1 | 2 | 5 | 72.02% (±3.25) | 6.68 (±0.08) | NF32 | 1 | 2 | 20 | 80.35% (±2.77) | 7.51 (±0.33) |
|
|
; Batch F21 was taken and studied for the best solvent system to get maximum PDE.
|