Research Article
Separation and Quantification of Eight Antidiabetic Drugs on A High-Performance Liquid Chromatography: Its Application to Human Plasma Assay
Table 2
Summary of precision and accuracy from QC samples in plasma ().
| | Compound | spiked concen. | Intraday | Interday | | (ng/mL) | | %RSD | Nominal (%) | | % RSD | Nominal (%) |
| | 53.7 | | 6.93 | 99.4 | | 6.79 | 98.6 | | ROS | 489.2 | | 4.13 | 98.4 | | 4.29 | 98.5 | | 1531.0 | | 8.51 | 99.3 | | 7.74 | 99.3 |
| | 48.9 | | 7.20 | 99.4 | | 6.02 | 98.3 | | PIO | 491.2 | | 3.30 | 99.8 | | 3.23 | 100.1 | | 1513.8 | | 8.90 | 98.5 | | 8.39 | 98.8 |
| | 50.6 | | 6.33 | 102.9 | | 7.85 | 100.6 | | GLP | 492.3 | | 3.74 | 102.5 | | 3.98 | 101.4 | | 1498.5 | | 7.25 | 100.5 | | 8.67 | 100.1 |
| | 46.8 | | 8.09 | 102.9 | | 8.50 | 102.9 | | GLC | 486.7 | | 3.20 | 101.2 | | 3.76 | 100.8 | | 1467.0 | | 8.05 | 100.8 | | 8.51 | 100.5 |
| | 49.2 | | 5.67 | 103.8 | | 7.77 | 99.3 | | REP | 493.4 | | 3.26 | 98.6 | | 3.55 | 98.7 | | 1502.7 | | 8.30 | 99.1 | | 6.16 | 98.9 |
| | 52.9 | | 5.99 | 97.7 | | 5.82 | 97.4 | | NGL | 478.6 | | 3.49 | 102.9 | | 3.44 | 102.4 | | 1439.6 | | 9.23 | 100.9 | | 8.41 | 100.1 |
| | 45.7 | | 7.04 | 99.3 | | 9.13 | 98.2 | | GLB | 478.5 | | 5.98 | 100.6 | | 4.35 | 100.2 | | 1452.0 | | 7.58 | 99.8 | | 6.74 | 99.9 |
| | 48.6 | | 5.90 | 101.0 | | 7.21 | 99.7 | | GLM | 490.5 | | 5.12 | 101.8 | | 4.93 | 100.4 | | 1477.5 | | 8.18 | 100.1 | | 7.88 | 99.5 |
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