Review Article
Thrombocytosis: Diagnostic Evaluation, Thrombotic Risk Stratification, and Risk-Based Management Strategies
Table 1
Causes of thrombocytosis (adapted from Harrison et al.).
| Clonal | Reactive | Spurious |
| Essential thrombocythemia | Infection | Microspherocytes | Polycythemia vera | Inflammation | Cryoglobulinemia | Primary myelofibrosis | Tissue damage | Neoplastic cell fragments | Myelodysplasia with del (5q) | Hyposplenism | Schistocytes | Refractory anemia with ringed | Post-operative | Bacteria | sideroblasts associated with | | | marked thrombocytosis (RARS-T) | | | Chronic myeloid leukemia | Iron deficiency | | Chronic myelomonocytic leukemia | Malignancy | | Atypical chronic myeloid leukemia | Hemolysis | | MDS/MPN-U | Drug effect | | POEMS syndrome | “Rebound” following myelosuppression | | Familial thrombocytosis | | |
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