Review Article
Metal Preferences of Zinc-Binding Motif on Metalloproteases
Table 4
Kinetic parameters for the hydrolysis of Arg-Arg-NA and metal contents of various metal-DPP IIIs.
| | Enzyme |
(×10−5 M) |
(s−1) |
(×104 M−1 s−1) | Metal content
(mol/mol of protein) |
| | Zn2+-DPP III | 8.1
(±1.0) | 7.1
(±0.2) | 8.8 | 0.8
(±0.1) | | Co2+-DPP III | 8.2
(±0.9) | 7.0
(±0.1) | 8.5 | 1.0
(±0.1) | | Cu2+-DPP III | 9.9
(±1.1) | 10.1
(±0.3) | 10.2 | 1.1
(±0.1) |
|
|
