Fluorescence biodistribution of activated NE680. Immediately after imaging, organs from 3 mice challenged with LPS/fMLP were excised and imaged on the FMT 2500 system using the reflectance mode. Regions of interest were drawn around each organ using the FMT software and the mean fluorescence (Counts/Energy) determined. Shown are means ± S.E.M. Insert shows an image of the fluorescence detected in different organs of a representative ALI mouse.