Research Article

Use of Pattern Recognition Analysis to Identify Underlying Relationships of Doxorubicin Derivatives Optimized for Breast Cancer Treatment

Figure 2

A dendrogram plot of hierarchical cluster analysis utilizing single linkage grouping method and Euclidean distance measurement. Note that this analysis clearly distinguishes drugs C, D, E, F, G, H, and I from the parent doxorubicin (drug A). Only drug B is determined to be highly similar to doxorubicin. Doxorubicin and drug B are join at supercluster 1, with remaining analogs associated to supercluster 2.
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