International Scholarly Research Notices

Research Article

Quercetin Treatment Ameliorates Systemic Oxidative Stress in Cirrhotic Rats

Table 2

Effects of quercetin (Q) on lipid peroxidation, antioxidant enzyme activities, and total nitrates on damage due to biliary obstruction.
ParametersExperimental groups
COCO + QCBDL + QCBDL + Q
TBARS (nmol/mg Hb)3.01 ± 0.222.46 ± 0.295.69 ± 0.23a3.87 ± 0.06b
SOD (U-SOD/mg protein)9.26 ± 0.558.26 ± 1.025.35 ± 0.53a9.35 ± 0.46
CAT (pmol/mg protein)0.1 ± 0.010.11 ± 0.010.05 ± 0.01a0.09 ± 0.01
GPx (mmol/min/mg Hb)3.45 ± 0.364.00 ± 0.612.15 ± 0.69a4.63 ± 0.66
Nitrates (μmol/L)125.6 ± 18.1110.5 ± 9.1264.99 ± 5.67a92.65 ± 5.75
CO: control; CBDL: common bile duct ligation; CO + Q and CBDL + Q: animals received a daily 50 mg/kg body i.p. injection of quercetin
Results represent the mean ± S.E.
aSignificant difference between the CBDL group and the CO, CO + Q, and CBDL + Q groups; P < 0.05.
bSignificant difference between the CBDL + Q group and the CO and CO + Q groups; 𝑃 < 0 . 0 5 .