Research Article

Diffusion Tensor Imaging for In Vivo Detection of Degenerated Optic Radiation

Figure 2

Glaucomatous optic nerve atrophy (case no. 1). Woman, 68 yr, OD/OS with primary open-angle glaucoma, in OS a parapapillary bleeding of the optic nerve head; topical medication: brimonidine, latanoprost, dorzolamide. (a) In both eyes (OS (left) > OD [right]) the automated perimeter showed predominantly superior visual field defects due to a loss of axons of the 3rd neuron. (b) The frequency doubling test indicated impaired spatial-temporal contrast sensitivity primarily in OS in the superior and temporal area as well as nasal near the center. (c) Typical signs of glaucomatous optic nerve atrophy were recorded by a nonmydriatic fundus camera that is in OS a small rim area, smaller inferior rim than temporal and a parapapillary bleeding (arrows). (d) DTI reveals significant rarefication of the optic radiation (arrows) in both occipital lobes (left > right). (e) Circumscribed microangiopathy (arrow) was diagnosed in the optic radiation based on MRI (FLAIR sequence).
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