International Scholarly Research Notices

Clinical Study

The Effect of Amlodipine Alone and in Combination with Atenolol on Bowel Habit in Patients with Hypertension: An Observation

Table 1

Effects of amlodipine alone and in combination with atenolol on bowel habit in patients with hypertension. SBM: spontaneous bowel movement. Results are expressed as mean±SD and absolute number.
ParametersAmlodipine (n=50)Amlodipine + atenolol (n=50)
Age (Yrs) (M±SD)54.14±11.3254.36±10.27
Male : Female23 : 2721 : 29
SBM/wk (M±SD)
 Before treatment8.64±4.47.84±2.5
 After treatment8.0±4.77.44±2.64
No of patients with SBM/wk<38*2
No. of patients with blood in stool5**0
No. of patients with straining/hard stool10***3
Duration of treatment (Months) (M±SD) 16.75±2.514.025±2.6
Dose of amlodipine
 No. of patients taking 5 mg OD2221
 No. of patients taking 10 mg OD2829
No. of patients taking isabgual54
*P=.045, Fisher's exact test, RR=4.00.
**P=.028, Fisher's exact test.
***P=.035, Fisher's exact test, RR=3.33.