Review Article

[Retracted] Immunopathology and Immunogenetics of Allergic Bronchopulmonary Aspergillosis

Table 1

Genetic risk factors in the development of allergic bronchopulmonary aspergillosis.

(i) HLA-DR restriction and HLA-DQ protection
 (a) HLA-DR2 restriction
    HLA-DRB1*1501 and *HLA-DRB1*1503
  (b) HLA-DR5
    HLA-DRB1*1104
  (c) HLA-DQ2 protective, decreased in ABPA
    DQB1*0201
(ii) IL-4RA polymorphisms
 (a) IL-4RA ile75val
(iii) IL-10 polymorphisms
  (a) Promoter −1082 GG genotype
(iv) Surfactant protein A2 (SP-A2) polymorphisms
  (a) SP-A2 ala91pro
(v) Cystic fibrosis transmembrane conductance regulator (CFTR) mutations
  (a) Heterozygous CFTR mutations in asthmatic patients with ABPA
(vi) Toll-like receptor (TLR) polymorphisms
  (a) TLR9 T-1237C polymorphism