Research Article
2-Pyrrolidinones and 3-Pyrrolin-2-ones: A Study on the Chemical Reactivity of These Structural Moieties
Scheme 7
Reagents and conditions: (a) (i) NaH (1.2 equiv), THF (r.t., 10 min), (ii) (Boc)2O (1.4 equiv, r.t., 20 min); (b) (i) KH (1.5 equiv), 18-crown-6 (0.5 equiv), THF (r.t., 5 min), (ii) Bn-Br (1.2 equiv, r.t., 10 min).
