Citrus/Cydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis: A Randomized Controlled Trial on Efficacy and Safety
Table 1
Baseline Characteristics (Full Analysis Set).
Variable
Citrus/Cydonia comp.
Gencydo
P value
()
()
Sex: no. (percentage)
Male
7 (58%)
2 (18%)
.049*
Female
5 (42%)
9 (82%)
Age (year) (sd)
36.8 (12.4)
36.9 (10.7)
.97
Height (cm) (sd)
177 (9.5)
170.6 (7.4)
.09
Weight (kg) (sd)
70.8 (11.2)
66.4 (8.9)
.3
Smokers: no. (percentage)
3 (25%)
1 (9%)
.31
Alcohol consumption: no. (percentage)
None
0 (0%)
3 (27.3%)
.15
Occasionally
11 (91.7%)
7 (63.6%)
Regularly
1 (8.3%)
1 (9%)
Ethnic origin: no. (percentage)
Caucasian
12 (100%)
9 (82%)
.12
Asian
0 (0%)
2 (18%)
Childbearing potential:number (percentage)
Capable
3 (60%)
8 (88.9%)
.31
Sterile
1 (20%)
1 (11.1%)
Postmenopausal
1 (20%)
0 (0%)
Blood pressure at screening (mm Hg) (sd)
120 (23)/ 73 (14)
104 (16)/ 72 (9)
.09/.77
Heart rate at screening (beats per minute)
72 (9)
70 (6)
.56
RAST grass pollen
3.7 (1.2)
3.9 (1.2)
.76
RAST birch pollen
2.2 (1.8)
2.3 (2.1)
.82
Usual SAR symptom severity during the pollen season (total score anamnestically) (sd)
Sneezing
2.1 (0.3)
2.3 (0.5)
Itching nose
1.9 (0.7)
2.1 (0.5)
Watery nasal discharge
1.9 (0.7)
2.1 (0.5)
Total score
5.9 (1.4)
6.5 (1.2)
.5
SAR symptom severity scores in the morning during the wash-out period (total score) (sd)
6.6 (4.5)
8.0 (4.6)
.55
SAR symptom severity scores in the evening during the wash-out period (total score) (sd)
