Citrus/Cydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis: A Randomized Controlled Trial on Efficacy and Safety
Table 4
Mean total symptom scores washout versus five weeks of treatment: morning and evening scores ().
Wash-out week mean (range)
Treatment week 5 mean (range)
Change (95% CI)
Morning scores
Citrus/Cydonia comp.
6.6 (2.1–15.2)
1.7 (0–6.4)
4.8 (1.7–7.9)
Gencydo
8.0 (0.6–14.3)
5.3 (0.3–11.4)
ns
Total
7.3 (0.6–15.2)
3.5 (0–11.4)
3.8 (1.3–6.3)
Evening scores
Citrus/Cydonia comp.
6.1 (1.7–11.8)
1.6 (0–5.0)
4.5 (1.7–7.2)
Gencydo
9.7 (0.3–16.5)
5.6 (0–15.0)
4.1 (0.4–7.8)
Total
8.0 (0.3–16.5)
3.6 (0–15.0)
4.3 (2.2–6.4)
Total symptom scores can vary from 0–24: 0–8: mild; 9–16: moderate; 17–24: severe.