Clinical Study

Citrus/Cydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis: A Randomized Controlled Trial on Efficacy and Safety

Table 4

Mean total symptom scores washout versus five weeks of treatment: morning and evening scores ( 𝑛 = 2 0 ).

Wash-out week mean (range)Treatment week 5 mean (range)Change (95% CI)

Morning scores
 Citrus/Cydonia comp.6.6 (2.1–15.2)1.7 (0–6.4)4.8 (1.7–7.9)
 Gencydo8.0 (0.6–14.3)5.3 (0.3–11.4)ns
 Total7.3 (0.6–15.2)3.5 (0–11.4)3.8 (1.3–6.3)

Evening scores
 Citrus/Cydonia comp.6.1 (1.7–11.8)1.6 (0–5.0)4.5 (1.7–7.2)
 Gencydo9.7 (0.3–16.5)5.6 (0–15.0)4.1 (0.4–7.8)
 Total8.0 (0.3–16.5)3.6 (0–15.0)4.3 (2.2–6.4)

Total symptom scores can vary from 0–24: 0–8: mild; 9–16: moderate; 17–24: severe.