Ex Vivo Evaluation of Insulin Nanoparticles Using Chitosan and Arabic Gum

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td align="left">Formulation code</td><td align="center">Mean diameter (nm, <svg height="10.9125" id="M16" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 35.099998 10.9125" width="35.099998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.9125)">
<g transform="translate(72,-63.27)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑛</tspan>
<tspan style="font-size: 12.50px; " x="9.6773224" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="21.71771" y="0">3</tspan>
</text>
</g>
</g>
</svg>)</td><td align="center">Polydispersity</td><td align="center">Zeta potential (mv)</td><td align="center">AE (%)</td><td align="center">Loading capacity</td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td align="left">F<sub>1</sub></td><td align="center"><span style="width: 56.849998px;"><svg height="12.05" id="M17" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 56.849998 12.05" width="56.849998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">9</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="21.530167" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="32.870388" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="39.121887" y="0">7</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center">0.48</td><td align="center"><span style="width: 64.662498px;"><svg height="12.175" id="M18" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 64.662498 12.175" width="64.662498" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.175)">
<g transform="translate(72,-62.26)">
<text transform="matrix(1,0,0,-1,-71.95,63.4)">
<tspan style="font-size: 12.50px; " x="0" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">6</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">4</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center"><span style="width: 72.474998px;"><svg height="12.05" id="M19" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 72.474998 12.05" width="72.474998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">8</tspan>
<tspan style="font-size: 12.50px; " x="51.624886" y="0">3</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center"><span style="width: 72.474998px;"><svg height="12.2375" id="M20" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 72.474998 12.2375" width="72.474998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.2375)">
<g transform="translate(72,-62.21)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">8</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">5</tspan>
<tspan style="font-size: 12.50px; " x="51.624886" y="0">6</tspan>
</text>
</g>
</g>
</svg></span></td></tr><tr><td align="left">F<sub>2</sub></td><td align="center"><span style="width: 56.849998px;"><svg height="12.05" id="M21" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 56.849998 12.05" width="56.849998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="21.530167" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="32.870388" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="39.121887" y="0">0</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center">0.26</td><td align="center"><span style="width: 64.662498px;"><svg height="12.05" id="M22" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 64.662498 12.05" width="64.662498" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">9</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center"><span style="width: 72.474998px;"><svg height="12.2375" id="M23" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 72.474998 12.2375" width="72.474998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.2375)">
<g transform="translate(72,-62.21)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">5</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">8</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="51.624886" y="0">1</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center"><span style="width: 80.287498px;"><svg height="12.05" id="M24" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 80.287498 12.05" width="80.287498" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="21.880251" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="30.907415" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="48.499138" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="51.624886" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="57.876389" y="0">3</tspan>
</text>
</g>
</g>
</svg></span></td></tr><tr><td align="left">F<sub>3</sub></td><td align="center"><span style="width: 56.849998px;"><svg height="12.05" id="M25" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 56.849998 12.05" width="56.849998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="21.530167" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="32.870388" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="39.121887" y="0">0</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center">0.25</td><td align="center"><span style="width: 64.662498px;"><svg height="12.2375" id="M26" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 64.662498 12.2375" width="64.662498" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.2375)">
<g transform="translate(72,-62.21)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">4</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">5</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">3</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center"><span style="width: 72.474998px;"><svg height="12.2375" id="M27" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 72.474998 12.2375" width="72.474998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.2375)">
<g transform="translate(72,-62.21)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">3</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">5</tspan>
<tspan style="font-size: 12.50px; " x="24.655916" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="35.996136" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="45.373386" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="51.624886" y="0">5</tspan>
</text>
</g>
</g>
</svg></span></td><td align="center"><span style="width: 80.287498px;"><svg height="12.175" id="M28" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 80.287498 12.175" width="80.287498" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.175)">
<g transform="translate(72,-62.26)">
<text transform="matrix(1,0,0,-1,-71.95,63.4)">
<tspan style="font-size: 12.50px; " x="0" y="0">1</tspan>
<tspan style="font-size: 12.50px; " x="6.2515001" y="0">6</tspan>
<tspan style="font-size: 12.50px; " x="12.503" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="15.62875" y="0">2</tspan>
<tspan style="font-size: 12.50px; " x="21.880251" y="0">8</tspan>
<tspan style="font-size: 12.50px; " x="30.907415" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="42.247639" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="48.499138" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="51.624886" y="0">7</tspan>
<tspan style="font-size: 12.50px; " x="57.876389" y="0">8</tspan>
</text>
</g>
</g>
</svg></span></td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Characteristic of the nanoparticles containing insulin for different formulations F<sub>1</sub>–F<sub>3</sub>.

International Scholarly Research Notices

tab3

Table 3

Table 3: Ex Vivo Evaluation of Insulin Nanoparticles Using Chitosan and Arabic Gum 