Development and Validation of Stability-Indicating HPTLC Determination of Tamsulosin in Bulk and Pharmaceutical Dosage Form

<table>A typical HPTLC densitogram of tamsulosin hydrochloride (<svg height="16.825001" id="M10" style="vertical-align:-4.77652pt" version="1.1" viewbox="0 0 66.4375 16.825001" width="66.4375" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,16.825)">
<g transform="translate(72,-58.54)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑅</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.7,60.22)">
<tspan style="font-size: 8.75px; " x="0" y="0">𝑓</tspan>
</text>
<text transform="matrix(1,0,0,-1,-52.82,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">=</tspan>
<tspan style="font-size: 12.50px; " x="12.027886" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="18.279387" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="21.405136" y="0">5</tspan>
<tspan style="font-size: 12.50px; " x="27.656635" y="0">2</tspan>
</text>
</g>
</g>
</svg>) in toluene : methanol : triethylamine (3.5 : 1.2 : 0.2, v/v) at 280 nm.</table>

Chromatography Research International

fig1

Figure 1

Figure 1: Development and Validation of Stability-Indicating HPTLC Determination of Tamsulosin in Bulk and Pharmaceutical Dosage Form 