International Journal of Proteomics

Research Article

Proteomic-Based Biosignatures in Breast Cancer Classification and Prediction of Therapeutic Response

Table 1

(a) Clinical characteristics of 11 TNBC tumors


LTQ Orbitrap sample ID	Patient age	Ethnicity	TR %	Response	T stage	Histological type	ER	PR	FISH R/G ratio	Neoadjuvant

#1	61	White	80	R	T3	IDC		−	1.10	TC
#2	29	Hispanic	−60	NR	T3	IDC	−	−	0.92	TC
#5	55	Hispanic	100	R (pCR)	T3	IDC	−	−	0.92	TC
#6	54	Hispanic	100	R (pCR)	T3	IDC	−	−	1.01	TC
#7	40	Asian	45	IR	T3	IDC	−	−	1.17	TC
#8	44	White		R (pCR)	T3	IDC	−	−	1.00	TC
#9	49	Hispanic	48	IR	T4	IDC	−	−	1.10	TC
#10	53	White	100	R (pCR)	T3	IDC	−	−	1.20	TC
#11	84	Asian	100	R (pCR)	T4	IDC	−	−	1.03	TC
#36	45	Hispanic	30	IR	T3	IDC	−	−	1.27	TC
#37	38	White	100	R (pCR)	T2	IDC	−	−	1.10	TC

^aLN positive without residual primary cancer.

(b) Clinical characteristics of 28 HER2+ tumors


LTQ Orbitrap sample ID	Patient age	Ethnicity	TRR %	Response	T stage	Histological type	ER	PR	FISH R/G ratio	Neoadjuvant

#17	38	White	40	IR	T3	IDC	+	−	12.4	TC
#18	63	Asian	100	R (pCR)	T3	IDC	+	−	12.7	TCH
#19	57	White	100	R (pCR)	T3	IDC	−	−	4.6	TC
#20	56	Asian	78.2	R	T4	IDC	+	−	10.71	TC
#21	51	Black	56	IR	T3	IDC	−	−	19.97	TCH
#22	31	White	45.5	IR	T3	IDC	+	+	2.2	TC
#23	55	White	80	R	T4	IDC	+	+	3.8	TC
#24	45	Asian	75	IR	T4	IDC	+	+	2.7	TCH
#25	42	Hispanic	63.5	IR	T4	IDC	+	−	2.5	TC
#26	50	White	67.1	IR	T3	IDC	−	−	2.41	TCH
#27	33	White	82.9	R	T3	IDC	+	+	3.03	TCH
#28	40	White	66.7	IR	T3	IDC	−	−	8.1	TC
#29	35	Hispanic		R (pCR)	T3	IDC	−	−	42.2	TCH
#30	44	White	97.3	R	T4	IDC	−	−	4.2	TC
#31	30	White	−7.7	NR	T3	IDC	+	−	5	TC
#32	57	White	25%	NR	T4	IDC	+	−	>4	TCH
#33	37	White	33.3	IR	T2	IDC	+	+	9.49	TC
#34	36	Black	25	NR	T3	IDC	−	−	5.1	TC
#35	42	White	60	IR	T2	IDC	+	+	4.5	TCH
#38	55	White	42.3	IR	T4	IDC	−	−	3.9	TCH
#39	47	White		R (pCR)	T3	IDC	+	+	>20	TCH
#40	50	Asian		R (pCR)	T3	IDC	+	+	4.19	TCH
#41	58	White	50	IR	T4	IDC	+	+	2.1	TCH
#42	40	Asian	60	IR	T2	IDC	−	−	16	TC
#43	37	White	−85.6	NR	T3	IDC	+	+	3.1	TC
#44	49	White		R (pCR)	T2	IDC	+	−	7.7	TCH
#45	55	Asian	92.6	R	T3	IDC	−	−	9.9	TC
#46	41	Hispanic	100	R (pCR)	T2	IDC	−	−	9.2	TC

^aLN positive and residual DCIS; ^bresidual DCIS only.