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Rank | Protein name | Accession no. | R/IR + NR mean | Subcellular location | Function |
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1 | Heat shock 70 kDa protein 8 isoform 1 | gi∣5729877 | 0.32 | | Stress response |
2 | Periostin precursor (PN) (osteoblast-specific factor 2) | gi∣93138709 | 0.31 | Nucleus | Transcription regulation |
3 | Cyclophilin A | gi∣1633054 | 0.41 | Secreted | Cell attachment adhesion and spreading |
4 | Tyrosine 3/tryptophan 5-monooxygenase activation protein | gi∣5803225 (+1) | 3.71 | Nucleus | Protein binding |
5 | Profilin | gi∣157838211 (+4) | 0.32 | Cytoplasm, cytoskeleton | Actin cytoskeleton organization |
6 | Cardiac muscle alpha actin 1 proprotein | gi∣4885049 | 0.08 | Cytoplasm, cytokeleton | actin filament-based movement, apoptosis |
7 | Beta actin | gi∣4501885 | 0.22 | Cytoplasm, cytokeleton | Cell motility |
8 | Caldesmon (CDM) | gi∣2498204 | 0.42 | Cytoplasm, cytokeleton | Actin- and myosin-binding protein |
9 | Tubulin 5 | gi∣7106439 | 0.19 | Cytosol | Major constituent of microtubules |
10 | Tropomyosin 2 (beta) isoform 1 | gi∣42476296 | 0.11 | Cytoplasm, cytokeleton | Binding to actin filaments |
11 | Actinin, 4 | gi∣12025678 | 0.11 | Nucleus, cytoplasm | Protein transport |
12 | Ras homolog gene family, member A (RhoA) | gi∣10835049 (+4) | 0.33 | Cytoplasm, cell membrane | Regulating a signal transduction pathway |
13 | Heterogeneous nuclear ribonucleoprotein K | gi∣13384620 | 0.33 | Cytoplasm, nucleus | Pre-mRNA-binding proteins |
14 | Tubulin 1 | gi∣6755901 | 0.36 | Cytosol | Major constituent of microtubules |
15 | Tropomyosin 4 | gi∣4507651 | 0.35 | Cytoplasm, cytokeleton | Binds to actin filaments |
16 | Complement component 1 inhibitor precursor | gi∣73858568 | 4.57 | Secreted | Complement pathway |
17 | ATP synthase, H+ transporting, mitochondrial F1 complex | gi∣4757810 | 0.43 | Mitochondrion | Proton-transporting ATP synthase complex assembly |
18 | Calnexin precursor | gi∣10716563 | 0.42 | Endoplasmic reticulum membrane, cell membrane | Calcium-binding protein |
19 | Eukaryotic translation elongation factor 1 alpha 1 | gi∣4503471 | 0.29 | Cytoplasm | Protein biosynthesis |
20 | Annexin I | gi∣4502101 | 0.25 | Nucleus, cytoplasm, membrane | Calcium/phospholipid-binding protein |
21 | Triosephosphate isomerase 1 | gi∣4507645 (+2) | 0.35 | Cytosol, nucleus | Fatty acid biosynthesis, gluconeogenesis, glycolysis, lipid synthesis |
22 | Cathepsin D preproprotein | gi∣4503143 | 0.35 | Lysosome | proteolysis |
23 | Alpha glucosidase II alpha subunit isoform 2 | gi∣38202257 | 0.19 | Cytosol | Glycan metabolism, N-glycan metabolism |
24 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein | gi∣4507949 (+1) | 0.42 | Nucleus | Protein binding |
25 | Thymosin 10 | gi∣10863895 | 0.42 | Cytoplasm, cytokeleton | cytoskeleton organization |
26 | Aconitase 2 precursor | gi∣4501867 | 0.44 | Mitochondrion | Carbohydrate metabolism, tricarboxylic acid cycle |
27 | Heterogeneous nuclear ribonucleoprotein D isoform a | gi∣14110420 | 0.48 | Nucleus, cytoplasm | Transcription regulation |
28 | Serine (or cysteine) proteinase inhibitor | gi∣32454741 | 0.25 | Secreted | Inhibits activated protein C, plasminogen activator |
29 | Lumican precursor | gi∣4505047 | 0.28 | Secreted | Binds to laminin |
30 | Apolipoprotein D | gi∣619383 | 2.86 | Secreted | Transport |
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