Mutation Analysis of the APC Gene in a Chinese FAP Pedigree with Unusual Phenotype
Figure 5
Methylation of the APC promoter was exclusively identified in the adenomas and carcinomas from Number 1. Primer sets for methylation-specific PCR are designated as methylated (M) and unmethylated (U) DNA. N (1): normal cancer-free tissue from Number 1. A (1): Adenoma from Number 1. C (1): Carcinoma from Number 1. +: Positive control. −: blank control.
