International Scholarly Research Notices

Research Article

Tissue Distribution and Associated Toxicological Effects of Decabrominated Diphenyl Ether in Subchronically Exposed Male Rats

Table 2

Whole body growth rates, and absolute and relative liver and kidney weight of the control rats and rats exposed to 10 or 50 mg/kg/d BDE-209 for 90 days.
ControlBDE-209 (10 mg/kg/d)BDE-209 (50 mg/kg/d)
Whole-body growth rates (%)a 1 . 5 7 ± 0 . 0 5 0 . 5 9 ± 0 . 1 2 ** 0 . 7 6 ± 0 . 0 7 **
Absolute liver weight (g) 1 3 . 6 9 ± 0 . 1 0 1 5 . 3 2 ± 0 . 8 4 1 4 . 3 8 ± 0 . 2 8
Absolute kidney weight (g) 3 . 2 4 ± 0 . 1 5 3 . 3 9 ± 0 . 1 4 3 . 3 3 ± 0 . 0 4
Relative liver weight (%)b 2 . 9 8 ± 0 . 0 5 3 . 0 6 ± 0 . 1 5 2 . 8 5 ± 0 . 0 7
Relative kidney weight (%)b 0 . 7 0 ± 0 . 0 3 0 . 6 8 ± 0 . 0 1 0 . 6 6 ± 0 . 0 3
Data are represented as mean ± SEM from six rats per group. aThe average growth rate after 90 days. bPercentage of total body weight. Statistically significant differences between the controls and treatments are indicated by ** for 𝑃 < 0 . 0 1 .