Susceptibility of Bifidobacteria of Animal Origin to Selected
Antimicrobial Agents
Table 1
Susceptibility of 8 B. animalis, 36. B. pseudolongum, and 73 B. thermophilum strains to selected antimicrobial agents as determined by the broth microdilution method using LSM-C medium.
Antibiotic
Species
MIC (μg/mL)
MIC range
MIC50
MIC90
Chloramphenicol
B. animalis
2–4
2
4
B. pseudolongum
1-2
1
2
B. thermophilum
0.5–2
1
2
Kanamycin
B. animalis
>128
>128
>128
B. pseudolongum
≥128
>128
>128
B. thermophilum
≥128
>128
>128
Linezolid
B. animalis
0.5–2
1
2
B. pseudolongum
0.5–2
1
1
B. thermophilum
0.5–1
0.5
1
Neomycin
B. animalis
32–>128
64
>128
B. pseudolongum
16–>128
64
>128
B. thermophilum
16–>128
128
>128
Quinupristin/
B. animalis
≤0.12
≤0.12
≤0.12
Dalfopristin
B. pseudolongum
≤0.12–0.25
≤0.12
0.25
B. thermophilum
≤0.12–0.25
≤0.12
0.25
Trimethoprim
B. animalis
≤0.12
≤0.12
≤0.12
B. pseudolongum
≤0.12–32
≤0.12
4
B. thermophilum
0.5–>128
8
128
MIC50 and MIC90: MICs (μg/mL) that inhibited 50% and 90% of the number of strains tested, respectively.